Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep117 | Adrenal and Cardiovascular Endocrinology | ECE2020

Diagnosis, treatment and survival of adrenocortical carcinoma: 28 years of experience

Catarino Diana , Silva Diana , Guiomar Joana , Moreno Carolina , Ribeiro Critina , Gomes Leonor , Fadiga Lucia , Lavrador Mariana , Vieira Inês , Caetano Rui , Figueiredo Arnaldo , Paiva Isabel

Introduction: Adrenocortical carcinoma is a rare endocrine disease characterized by an aggressive behaviour with a poor prognosis. Clinical experience, even with a little number of patients, has enhanced knowledge about this malignancy, in most cases challenging.Objective: Characterization of patients with adrenocortical carcinoma followed at the endocrine department of a hospital centre, between 1991 and 2019.Methods: Retrospectiv...

ea0070aep116 | Adrenal and Cardiovascular Endocrinology | ECE2020

Adjuvant mitotane therapy: Predictive factors of response in adrenocortical carcinoma

Alexandra Festas Silva Diana , Reis Guiomar Joana , Catarino Diana , Moreno Carolina , Gomes Leonor , Ribeiro Cristina , Fadiga Lúcia , Vieira Inês , Lavrador Mariana , Caetano Rui , Figueiredo Arnaldo , Paiva Isabel

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor, with a poor prognosis and median survival of 3–4 years. Complete surgical resection is the only possibility of cure. The rate of post-surgical recurrence is high, so adjuvant treatment with mitotane plays a key role.Objectives: To evaluate predictive factors of response to adjuvant treatment with mitotane in monotherapy in patients that underwent surgical resection of ACC....